13 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Secondary ... Clinically Relevant HES ... disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Differential Diagnosis Algorithm ... • Loose anagen syndrome ... to Skin Disease ... Congenital hair shaft ... #Diagnosis #Algorithm
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... leakage of RBC's secondary ... Kasabach-Merritt syndrome ... Differential #Diagnosis #hematology ... #rheumatology #
Focal / Localized Hair Loss (Alopecia) - Differential Diagnosis Algorithm

Scarring - Irreversible-biopsy required
 - Infectious
Differential Diagnosis Algorithm ... decalvans - Secondary ... to Skin Disease ... Congenital hair shaft ... Focal #Localized #dermatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... • Screen for secondary ... symptoms (eg, skin ... #diagnosis #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... blood eosinophilia Secondary ... Causes: - Allergic disorders ... - Immunologic disorders ... #diagnosis #hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... hematological disorders ... reticularis & skin ... Type III Often Secondary ... classification #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
cryoglobulinemia Associated Disorders ... Cryoglobulinemia • TTP, HUS ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... hemolytic-uremic syndrome ... nose (epistaxis), skin ... (alopecia, purpura ... loss, causing secondary
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... and permanent alopecia ... Non-autoimmune rheumatologic ... • Nonscarring alopecia ... Erythematosus #Diagnosis #Rheumatology