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diagnosis differential dermatology alopecia focal generalized hairloss pruritus systemic diffuse disorders eczematous eosinophil leukemia localized oncology petechiae petechial physicalexam rash
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
Diagnosis Algorithm ... Primary Eosinophilia ... Secondary Eosinophilia ... GI, lung, skin), ... #allergy
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Screen for secondary ... causes of eosinophilia ... are asthma, allergy ... symptoms (eg, skin ... Differential #diagnosis #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... Causes == Primary ... #secondary #systemic ... #generalized #dermatology ... #causes
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
pass = Dangerous secondary ... Chronic & Rx-related Secondary ... ESRD & CAD • Eosinophilic ... 3rd pass = Primary ... #allergy
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Differential Diagnosis Algorithm ... decalvans - Secondary ... to Skin Disease ... Congenital hair shaft ... #causes
Eczematous Skin Rash - Differential Diagnosis Algorithm Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated • Atopic Dermatitis
Eczematous Skin ... Differential Diagnosis Algorithm ... Secondary to venous ... anyone - Allergic ... #causes
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Abnormalities in primary ... or secondary hemostasis ... cryoglobulins • Skin ... #Causes #dermatology
Focal / Localized Hair Loss (Alopecia) - Differential Diagnosis Algorithm Scarring - Irreversible-biopsy required - Infectious
Differential Diagnosis Algorithm ... decalvans - Secondary ... to Skin Disease ... Congenital hair shaft ... #causes
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... Diagnosis Algorithm ... #Pruritus #secondary ... #causes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• (Peripheral eosinophilia ... + distinctive primary ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology
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