11 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Syndrome • Secondary ... disorders • Diagnosis ... #eosinophilia # ... eosinophils #diagnosis ... #management #algorithm
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Diagnosis Algorithm ... Primary Eosinophilia ... : • Primary hypereosinophilic ... Secondary Eosinophilia ... GI, lung, skin),
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm ... • Screen for secondary ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Generalized Differential Diagnosis ... Algorithm - Systemic ... == Primary Skin ... #secondary #systemic ... #Algorithm #causes
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
) Differential Diagnosis ... Algorithm DIFFUSE ... to Skin Disease ... Congenital hair shaft ... #Algorithm #causes
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... Abnormalities in primary ... or secondary hemostasis ... cryoglobulins • Skin
Focal / Localized Hair Loss (Alopecia) - Differential Diagnosis Algorithm

Scarring - Irreversible-biopsy required
 - Infectious
- Differential Diagnosis ... Algorithm Scarring ... decalvans - Secondary ... to Skin Disease ... Congenital hair shaft
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... Diagnosis Algorithm ... #Pruritus #secondary ... #generalized #dermatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Vaginal dryness • Primary ... other diseases • Secondary ... Nephrogenic DI Hematologic ... #Diagnosis #Management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• (Peripheral eosinophilia ... + distinctive primary ... bone marrow and secondary ... CLL -> Invade Skin ... #Oncology #Diagnosis