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diagnosis biliary oncology pbc alkaline alopecia causes cholangitis dermatology differential diffuse focal hairloss hyophosphatasia leukemia low mds myelodysplasia myelodysplastic phosphatase
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... Algorithm Symptoms ... Elevated ALP 2. ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... Examination: • Skin ... obstruction • ALP ... diagnosis #workup #hepatology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Differential Diagnosis Algorithm ... decalvans - Secondary ... to Skin Disease ... Congenital hair shaft ... areata • Secondary
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• recurrent fractures ... pain • loss of secondary ... pain - Frequent fractures ... • Elevation of urinary ... Hyophosphatasia #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview: ALL ... + distinctive primary ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... involve one, two, or all ... DDX: Rule Out Secondary ... characteristic feature ... Syndromes #diagnosis #hematology
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