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diagnosis oncology management agglutinin alkaline aplastic causes differential disease disorders hemeonc hemolytic hemophagocytic hlh hyophosphatasia leukemia lymphohistiocytosis mentzerindex myelodysplasia myelodysplastic
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
in 1923 Low ALP ... pain • loss of secondary ... • Pernicious anemia ... , ↓ALP → Low ... Hyophosphatasia #hepatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
15% of AIHA Primary ... Secondary Cold ... originate from a low-grade ... Blood smear - RBC ... #hematology #diagnosis
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... a decrease in all ... Leukopenia is primarily ... These causes could ... Satyendra Dhar MD
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... Anticonvulsants - Gold ... • ↓ WBC • ↓ ... may result from low ... #oncology #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
practices that could ... changes), high MCV anemia ... not required in all ... unclear, or if a primary ... Causes #Workup #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... involve one, two, or all ... DDX: Rule Out Secondary ... characteristic feature ... Syndromes #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... + distinctive primary ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Types of HLH • Primary ... STX11, STXBP2 • Secondary ... - Cytopenias (anemia ... Low/absent NK-cell ... Diagnosis #Management #Hematology
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