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diagnosis differential oncology causes dermatology generalized leukemia pruritus workup agglutinin chronic cold disease erythematosus hemeonc hemolytic hemophagocytic hlh lupus lymphocytic
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
== Primary Skin ... Skin Lesion / Systemic ... renal failure/uremia ... Hyperthyroidism CBC ... #secondary #systemic
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Differential Diagnosis Algorithm ... Reticulocytosis • Primary ... Hypersplenism • Secondary ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... + distinctive primary ... bone marrow and secondary ... -> Invade Skin: ... #Leukemia #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Hepatomegaly • Skin ... Scoring system: ... • Neutropenia, anemia ... workup #oncology #hematology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Pancytopenia is a hematologic ... a decrease in all ... peripheral blood cell ... Leukopenia is primarily
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... Hyperthyroidism CBC ... #Pruritus #secondary ... #systemic #generalized
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
15% of AIHA Primary ... Secondary Cold ... lymphoproliferative disorder Secondary ... Blood smear - RBC ... #hematology #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Entities That Can Feature ... Lymphoma (HCV) • CLL ... Alpha & Mu) Skin ... (-) hemolytic anemia ... Paraproteinemias #Hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... frequently affected systems ... Better call hematology ... else is driving RBC ... #workup #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
count (anemia) ... just beneath the skin ... DDX: Rule Out Secondary ... characteristic feature ... Syndromes #diagnosis #hematology
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