Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
- Decreased/NormaI Reticulocytosis
• Marrow Aplasia
• Marrow Infiltration
- Increased Reticulocytosis
• Primary Hypersplenism
• Secondary (e.g. RA, SLE, PRV, Chronic)
Normal/lncreased WBCs
- Polychromatic Macrocytes, Normal RBCs
• Acute Bleed
• Hemolysis
- Polychromatic Macrocytes, RBC Spherocytes, RBC Fragments
• Microangiopathic Hemolytic Anemias (MAHA)
- Abnormal RBCs - Sickle Cells, Target Cells
• Hemoglobinopathy
- Normal Reticulocytosis
• Renal Failure
• Inflammation
• Cancer
• Hypothyroid
• Pregnancy
• Early Iron Deficiency
#Normocytic #Anemia #Differential #Diagnosis #Algorithm #Causes #Hematology
