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diagnosis differential causes oncology dermatology alopecia hairloss localized management syndrome diffuse disorders eosinophil eosinophils hes hypereosinophilia hypereosinophilic lad leukemia lymphadenopathy
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
Syndrome • Secondary ... and Treatment Algorithm ... Syndrome #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm ... • Screen for secondary ... symptoms (eg, skin ... #Disorders #Algorithm ... Differential #diagnosis #hematology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Differential Diagnosis Algorithm ... decalvans - Secondary ... to Skin Disease ... Congenital hair shaft ... areata • Secondary
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Differential Diagnosis Algorithm ... Tularemia • Secondary ... #Localized #Focal ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Focal / Localized Hair Loss (Alopecia) - Differential Diagnosis Algorithm Scarring - Irreversible-biopsy required - Infectious
Focal / Localized ... decalvans - Secondary ... to Skin Disease ... Congenital hair shaft ... #Localized #dermatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... in primary or secondary ... Urinalysis • Fecal ... cryoglobulins • Skin ... #Causes #dermatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Entities That Can Feature ... Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Episodic angioedema+eosinophilia ... Paraproteinemias #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• (Peripheral eosinophilia ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
lacrimal glands: • Focal ... Lacrimal swelling • Skin ... other diseases • Secondary ... Nephrogenic DI Hematologic ... Sjogrens #Syndrome #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... DDX: Rule Out Secondary ... characteristic feature ... Syndromes #diagnosis #hematology
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