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diagnosis rheumatology differential management vasculitis arthritis behcet chronic classification cll disease leukemia lupus lymphocytic manifestations mucocutaneous oncology pathophysiology polychondritis relapsing
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... Oral aphthae : SLE ... • Arthritis: SLE ... diagnosis #management #signs ... #symptoms #rheumatology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
cells -> Incr local ... inflammation on skin ... > Mouth, Nasal Ulcers ... pathophysiology #diagnosis #signs ... #symptoms #complications
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Airways disease, Complications ... of DMARDs • Skin ... gastritis and peptic ulcer ... Rheumatoid #Arthritis #RA ... #Signs #Symptoms
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Hepatomegaly • Skin ... plaques, nodules, ulcers ... workup #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
livedo reticularis, ulcers ... genital aphthous ulcers ... Presentation - Systemic Symptoms ... purpura: strong sign ... vasculitis, and SLE
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... genital aphthous ulcers
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... + Nonspecific symptoms ... • Inner ear • Skin ... cases such as: • SLE ... Multiple myeloma Complications
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