13 results
Algorithm for Diagnosis of the Petechial / Purpuric Rash

Febrile/Toxic, Palpable: 
 - Meningococcaemia, Disseminated Gonococcal Infection,
Algorithm for Diagnosis ... / Purpuric Rash ... - Autoimmune Vasculitis ... #Purpuric #Petechiae ... #Dermatology #Skin
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
Petechial/Purpuric ... Nonpalpable purpura ... /purpura with fever ... #Diagnosis #Dermatology ... #Purpural #Purpuric
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... OF NON-PALPABLE PURPURA ... Acute Infectious Purpura ... • Pigmented Purpuric ... /HSP • Cryoglobulinemia
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Lupus Nephritis, Cryoglobulinemia ... Henoch-SchonIein Purpura ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm ... #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
, Palpable purpura ... • Palpable purpura ... Vesicles overlying purpuric ... Henoch-Schönlein purpura ... • Mixed cryoglobulinemia
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Small Vessel: Petechiae ... , Palpable purpura ... Urticarial/LCV) - Cryoglobulinemic ... - GPA Cutaneous ... #rheumatology #
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Infection - Vasculitis ... Henoch Schonlein Purpura ... Non-Palpable Rash: - Purpura ... RA, Sjogren's, GPA
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura ... - Diagnostic Algorithm ... #Diagnosis #Dermatology ... #Rash #Petechiae ... #Purpura #Palpable
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
correlations • Purpura ... (5%): PAN > GPA ... , EGPA • Solid ... hemopathies (4%) • Cryoglobulinemia ... #dermpath #dermatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... triad of Palpable purpura ... - GPA, EGPA, microscopic ... Henoch-Schönlein purpura ... classification #rheumatology