22 results
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis ... Weakness, fatigue, nausea ... hyponatremia, hyperkalemia ... likely: • High ... #Algorithm #endocrinology
Causes of Hypercalcemia
Parathyroid hormone–dependent
Primary hyperparathyroidism
Familial hypocalciuric hypercalcemia
Lithium-associated
Tertiary hyperparathyroidism
Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... Genetic disorders (e.g ... thyrotoxicosis, adrenal insufficiency ... #Causes #Differential ... #Diagnosis #Endocrinology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... phlebotomy High ... Intracellular Shift ... deficiency • Renal insufficiency ... #causes #potassium
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... phlebotomy High ... Intracellular Shift ... deficiency • Renal insufficiency ... #causes #potassium
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
potassium and ECG ... blocks, QRS axis shift ... #potassium #high ... #diagnosis #management ... #algorithm #treatment
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
: Most Common Cause ... Adrenalitis Other causes ... Hyperkalemia is ... Give 250 mcg of ... #Management #Endocrinology
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... unclear (often the case ... Stim test is 250 mcg ... Measure ACTH: - High ... Stimulation #Test #Endocrinology
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
Overview Hypoxia - insufficient ... maybe sepsis) - High ... PaO2, High SvO2 ... #differential #diagnosis ... #causes #pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... WBC count cause ... hydration - Hyperkalemia ... unless worrisome EKG ... Syndrome #TLS #diagnosis
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
- Differential Diagnosis ... Dermatomyositis) AKI - Pathophysiology ... Shift of extracellular ... Dialysis for severe hyperkalemia ... Management #Summary #causes