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management hematology differential nephrology causes algorithm tls hypokalemia lysis neurology tumor workup classification erythematosus hemeonc lupus rhabdomyolysis signs sle summary
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
and ECG changes ... blocks, QRS axis shift ... #potassium #high ... #diagnosis #management ... #algorithm #treatment
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
patients with hypokalemia ... creatinine) • Cell shift ... #hypokalemia ... #urine #potassium ... differential #algorithm #diagnosis
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
8.0 mg/dL • Potassium ... Calcium ≤ 7.0 mg/dL Clinical ... hydroxide • Hyperkalemia ... #TLS #diagnosis ... #management #oncology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... phlebotomy High ... Intracellular Shift ... - Tumor lysis syndrome ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... phlebotomy High ... Intracellular Shift ... - Tumor lysis syndrome ... #high #nephrology
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... ) occur in high ... malignancies Treatments ... with Ca only if EKG ... #TLS #oncology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Dermatomyositis Clinical ... Shift of extracellular ... Monitor potassium ... #Differential #Diagnosis
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
- Differential Diagnosis ... iniury, Compartment syndrome ... Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... Spontaneous if high ... hydration - Hyperkalemia ... unless worrisome EKG ... #TLS #diagnosis
Tumor Lysis Syndrome - Workup and Management Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
≥ 8 mg/dL • Potassium ... of the above Treatment ... of Clinical TLS ... #diagnosis #management ... #oncology
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