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differential management causes nephrology algorithm cardiology hypokalemia lysis oncology rhabdomyolysis tumor classification complexes ekg elevation evaluation hematology k leukostasis premature
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
of Tumor Lysis Syndrome ... (TLS) and Treatment ... 8.0 mg/dL • Potassium ... hydroxide • Hyperkalemia ... #TLS #diagnosis
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
and ECG changes ... blocks, QRS axis shift ... #potassium #high ... #diagnosis #management ... #algorithm #treatment
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
patients with hypokalemia ... creatinine) • Cell shift ... #hypokalemia ... #urine #potassium ... differential #algorithm #diagnosis
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... phlebotomy High ... Intracellular Shift ... - Tumor lysis syndrome ... #high #nephrology
Causes of Hyperkalemia - Differential Diagnosis Framework • Cellular Shift: - Exercise
- Differential Diagnosis ... Framework • Cellular Shift ... Increased production: TLS ... #Causes #potassium ... #high
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... ) occur in high ... malignancies Treatments ... with Ca only if EKG ... #TLS #oncology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... phlebotomy High ... Intracellular Shift ... - Tumor lysis syndrome ... #high #nephrology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... Spontaneous if high ... hydration - Hyperkalemia ... unless worrisome EKG ... #TLS #diagnosis
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
- Differential Diagnosis ... HIV, Influenza, TSS ... Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... HIV, Influenza, TSS ... Shift of extracellular ... Monitor potassium ... #Differential #Diagnosis
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