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diagnosis management signs causes differential neurology algorithm barre bulimianervosa complications cushings encephalopathy endocrinology gbs gitelman guillain hematology hypercortisolism intercellularshift leukostasis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Dermatomyositis Clinical ... • LDH ↑ • Hyperkalemia ... Shift of extracellular ... Dialysis for severe hyperkalemia ... causes #treatment #nephrology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... • Cell Lysis (e.g ... Tumor Lysis Syndrome ... • Digoxin #Hyperkalemia ... IntercellularShift #Nephrology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... : • Pathophysiology ... hydration - Hyperkalemia ... unless worrisome EKG
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
tubule (DCT) Clinical ... Family history of hypokalemia ... • Unexplained hypokalemia ... pressure Labs: • Hypokalemia ... #Hypokalemia
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Blood transfusion, Hypercalcemia ... Etiology: • Pathophysiology ... Neurological symptoms ... • EEG: With persistent ... diagnosis #management #neurology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... hyperphosphatemia, hypercalcemia ... renal failure Clinical ... of diagnosis (e.g ... : (distinct symptoms
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
Cushing's Syndrome ... Diagnosis and Clinical ... Cataracts Labs: Hypokalemia ... #Cushings #Syndrome ... Diagnosis #signs #symptoms
Bulimia Nervosa: Complications GASTROINTESTINAL • Dehydration & inability to digest food -> Constipation • Recurrent vomiting exposes
• Boerhaave syndrome ... ) • Overall: hypokalemia ... Complications #pathophysiology ... diagnosis #signs #symptoms ... #psychiatry
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... transplantation CLINICAL ... than one after symptom ... the underlying pathophysiology ... Guillain #Barre #Syndrome
Serotonin Syndrome: Pathogenesis and Clinical Findings Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Serotonin Syndrome ... drugs of abuse (e.g ... #Pathophysiology ... #Psychiatry #Diagnosis ... #Signs #Symptoms
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