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diagnosis management differential rheumatology causes erythematosus hemeonc hemophagocytic hlh leukostasis lupus lymphohistiocytosis lysis myopathy myositis potassium sarcoidosis sle symptoms syndrome
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... WBC >100k, + lab signs ... hydration - Hyperkalemia ... unless worrisome EKG ... diagnosis #management #hematology
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
extracellular shift ... Tubulointerstitial diseases: syßtemic ... Autoimmune: Addison's ... Differential #Diagnosis #High ... #Potassium #Classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... complements and a high ... Skin Disease Classification ... disease • Non-autoimmune ... deficiencies • Autoimmune
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Epidemiology 1) High ... survival is 93-95% Pathophysiology ... the lymphatic system ... hyperphosphatemia, hypercalcemia ... Diagnosis #Management #Signs
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Lymphohistiocytosis (HLH) High ... of the immune system ... Presentation • Common Signs ... Pathophysiology ... Diagnosis #Management #Hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Aldolase levels • EMG ... papules and Gottron sign ... ) • Shawl sign ... • Conduction system ... weakness • Very high
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