6 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
in 1923 Low ALP ... collection with EDTA Pathophysiology ... , ↓ALPLow ... mineralization Symptoms ... Hyperlipidemia - Hypercalcemia
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and high ... , Elevated Cr, Low ... hydration - Hyperkalemia ... unless worrisome EKG
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
Saline (NS) - Comparison ... Is Dangerous in Hyperkalemia ... transcellular shift ... densa receives high ... #pharmacology #
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
we introduce a high ... of essentially all ... causes Hyperkalemia ... The high CL- content ... diagnosis #treatment #pharmacology
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
Binging on foods high ... hormonal imbalances (low ... ) • Overall: hypokalemia ... Complications #pathophysiology ... diagnosis #signs #symptoms
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Lymphohistiocytosis (HLH) High ... • In all patients ... Common Signs and Symptoms ... Pathophysiology ... Low/absent NK-cell