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management potassium criticalcare crystalloids differential druginduced evaluation foamed hematology hypokalemia leukostasis lysis medications physiology syndrome tls tumor
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC ... shift of K (Succinylcholine ... #differential #diagnosis ... #pathophysiology ... #pharmacology #
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
potassium and ECG ... blocks, QRS axis shift ... #potassium #high ... #diagnosis #management ... #algorithm #treatment
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and high ... hydration - Hyperkalemia ... unless worrisome EKG ... Syndrome #TLS #diagnosis
Evaluation and Management of Hypokalemia Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
warranting urgent treatment ... electrocardiography (ECG ... transcellular shifts ... #Diagnosis #Hypokalemia ... #Evaluation #Algorithm
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 The crusade against “Ab”Normal Saline continues. This is a non-physiologic fluid that can harm our
we introduce a high ... causes Hyperkalemia ... The high CL- content ... criticalcare #management #diagnosis ... #treatment #pharmacology
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