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diagnosis differential algorithm macrocytosis cell chronic crisis fatigue gammopathies hypokalemia intercellularshift macrocytic management mgus microcytic monoclonal multiplemyeloma plasmacytoma renal rheumatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Increased Requirement (e.g ... #Macrocytosis #elevatedMCV ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Iron Deficiency (Eg ... Causes: Chronic ... #Macrocytosis #elevatedMCV ... #Hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Liver Failure • Hypercalcemia ... Neoplastic / Hematologic ... • Anemia • ... • Drug Abuse (e.g
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Gammopathies C - HyperCalcemia ... 40 ml/min A - Anemia ... Causes of false- ... MGUS #diagnosis #hematology ... #oncology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... Intercellular Shift ... Transcellular Shift ... • Cell Lysis (e.g ... IntercellularShift #Nephrology
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Transcellular Shifts ... megaloblastic anemia ... #Causes #differential ... #diagnosis #nephrology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
microangiopathic hemolytic anemia ... (short-acting, e.g ... • Refractory cases ... Renal #Crisis #rheumatology ... #nephrology #diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
red bone marrow, e.g ... • No CRAB - no anemia ... , hypercalcemia, ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology
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