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management table treatment algorithm binding diagnosis high medications action agents causes differential diuretics effects kayexelate kbinders kdigo lactated lr normal
Key Characteristics of Old and New Potassium-Binding Agents - Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd #Potassium #Binding #KBinders #Kayexelate
#Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia ... #Nephrology #Agents
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Potassium Binders ... #Hyperkalemia # ... treatment #pharmacology ... #table #comparison ... #nephrology
Diuretics sites of action on the nephron 1) Acetazolamide (carbonic anhydrase inhibitor) 2) Osmotic diuretics (e.g. mannitol) 3) Loop
action on the nephron ... Metolazone) 5) Potassium-sparing ... triamterene) #nephron ... #diuretics #pharmacology ... #nephrology #medications
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison ... #binders
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... • Consider K+ binder ... and ECG changes ... blocks, QRS axis shift ... #potassium #high
Characteristics of Commonly Used Phosphate Binders Aluminum - Potent and effective - Useful for
Used Phosphate Binders ... #Phosphate #Binders ... #Table #Comparison ... #Pharmacology # ... Nephrology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
Saline (NS) - Comparison ... 130 mEq/L • Potassium ... Is Dangerous in Hyperkalemia ... transcellular shift ... #pharmacology #
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
• LDH ↑ • Hyperkalemia ... Shift of extracellular ... fluid/Lactated ringers ... Monitor potassium ... causes #treatment #nephrology
KDIGO Treatment algorithm for management of acute hyperkalemia in the emergency department • Place on cardiac
management of acute hyperkalemia ... monitor 12-lead ECG ... • Consider K+ binder ... algorithm #treatment #potassium ... #high #nephrology
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