39 results
Emergency Management of Hyperkalemia in Adults
Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach
 •
Management of Hyperkalemia ... clinical scenario, ECG ... Gluconate IV Shift ... Consider cause of hyperkalaemia ... recurrence #Hyperkalemia
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... MunerMohamed1 #hyperkalemia ... pathophysiology #pharmacology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... and sodium • Dosing ... binds magnesium • Dosing ... and calcium • Dosing ... #medications #pharmacology
Ketamine Dosing

0.1 — 0.3 mg/kg Analgesia 
0.2 - 0.5 mg/kg Recreational 
0.4 — 0.8 mg/kg Partially
Ketamine Dosing ... 0.1 — 0.3 mg/kg ... 0.2 - 0.5 mg/kg ... #Ketamine #Dosing ... Partially #Fully #Pharmacology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... Intracellular Shift
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... potassium and ECG ... blocks, QRS axis shift ... , asystole #hyperkalemia
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... Intracellular Shift
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... Treatment Algorithm ECG ... injury, etc) ECG ... cardiac membrane Shift ... not quickly) #Hyperkalemia
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
: Treatment of Hyperkalemia ... oral suspension DOSING ... who have chronic hyperkalemia ... carry the risk of hyperkalemia ... #Pharmacology
Adult Vancomycin Guidelines
The information below provides general dosing guidelines for vancomycin. A maintenance regimen of 15-20
provides general dosing ... regimen of 15-20 mg/kg ... is the accepted dosing ... #Management #Pharmacology ... #Vancomycin #Dosing