25 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Agents - Dr. ... edgarvlermamd #Potassium ... KBinders #Kayexelate #Comparison ... Pharmacology #Patiromer #HyperKalemia ... #Nephrology #Agents
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... minutes) Decrease potassium ... • IV Fluids Shift ... LouLectures #Hyperkalemia ... #management #potassium
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat ... Hyperkalemia Sodium ... to moderate); hypokalemia ... Hypomagnesemia; hypokalemia ... #Binding #Hyperkalemia
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
the Treatment of Hyperkalemia ... redistributive hyperkalemia ... on ECG, severe hyperkalemia ... of hyperkalemia ... #Hyperkalemia #
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
8.0 mg/dL • Potassium ... Calcium ≤ 7.0 mg/dL Clinical ... other symptomatic hypocalcemia ... hydroxide • Hyperkalemia ... treatment • Hypocalcemia
Hyperkalemia Management Algorithm
 • Treat the cause & optimize hemodynamics and ventilation
 • Reconsider treatment leadingto
Hyperkalemia Management ... treatment leadingto hyperkalemia ... and parenteral potassium ... Intracellular K+ Shift ... / Removal #Hyperkalemia
Emergency Management of Hyperkalemia in Adults
Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach
 •
of Hyperkalemia ... Treatment guided by clinical ... Gluconate IV Shift ... Consider cause of hyperkalaemia ... recurrence #Hyperkalemia
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... for Management ... of Hyperkalemia ... #Hyperkalemia # ... pharmacology #table #comparison
Hyperkalemia management algorithm 2023-2024 based on UKKA and KDIGO guidelines.

#hyperkalemia #electrolytes #algorithm #emergency #management

Notes:

(1) Up to
Hyperkalemia management ... #hyperkalemia #electrolytes ... Up to half of hyperkalemia ... patients with extreme hyperkalemia ... for refractory hyperkalemia
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... Dialysis Serum potassium ... blocks, QRS axis shift ... , asystole #hyperkalemia ... #potassium #high