38 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... MunerMohamed1 #hyperkalemia ... differential #diagnosis #pathophysiology ... #pharmacology #
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift ... Refeeding Syndrome #Hypokalemia ... potassium #low #pathophysiology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... Hypomagnesemia; hypokalemia ... disturbances (including hypokalemia ... Potassium #Binding #Hyperkalemia
Emergency Management of Hyperkalemia in Adults
Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach
 •
Management of Hyperkalemia ... - 6.4 mmol/L - Treatment ... Gluconate IV Shift ... Consider cause of hyperkalaemia ... recurrence #Hyperkalemia
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
of Hyperkalemia ... disturbances, shift ... redistributive hyperkalemia ... provoke rebound hypokalemia ... , and Table 3 summarizes
Emergency Therapy of Hyperkalemia
Therapy - Dose and Route - Onset of Action - Duration of Effect
Emergency Therapy of Hyperkalemia ... Hemodialysis #Hyperkalemia ... #management #pharmacology ... #table #treatment
Causes of Hypokalemia

Hypokalemia results from abnormal losses, transcellular shifts, or insufficient intake (Table 1).6–8 Abnormal losses
Causes of Hypokalemia ... Hypokalemia results ... transcellular shifts ... insufficient intake (Table ... sole cause of hypokalemia
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... • IV Fluids Shift ... LouLectures #Hyperkalemia
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Kayexelate #Comparison #Table ... #Pharmacology # ... Patiromer #HyperKalemia
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
S - Shock H - Hyperkalemia ... other findings of hyperkalemia ... ) BRASH Treatment ... of hyperkalemia ... diagnosis #management #pathophysiology