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diagnosis management neurology causes differential hypokalemia algorithm amyotrophic emergencies encephalopathy evaluation gravis hematology hemeonc lateral leukostasis lysis myasthenia oncologic oncology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Compartment syndrome ... or compartment syndrome ... Shift of extracellular ... Treatment of underlying ... #nephrology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
WBC >100k, + lab signs ... organ damage • Treatment ... Low calcium • Treatment ... hydration - Hyperkalemia ... treatment (no calcium
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
thyroid, Sjogren syndrome ... Generalized fatigue - ALS ... test - Cogan sign ... - Peek sign ... diagnosis #management #neurology
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Transcellular Shifts ... plasma insulin (treatment ... or induced) #Hypokalemia ... differential #diagnosis #nephrology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of UMN and LMN signs ... Upper extremity, lower ... EMG: LMN Signs in ... diagnosis column Treatment ... Lateral #Sclerosis #neurology
Evaluation and Management of Hypokalemia Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
search for warning signs ... warranting urgent treatment ... transcellular shifts ... Identification and treatment ... hypomagnesemia are also
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 Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Blood transfusion, Hypercalcemia ... edema visualized as ... epilepticus Treatment ... underlying cause • Treatment ... BP lowering - Lower
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS ... low Ca - q8 h TLS ... 100 000 (can be lower ... plasmapheresis Hypercalcemia ... → no immediate treatment
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