44 results
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Differentiating Gitelman ... syndrome from Bartter ... #syndrome #Bartter ... #Algorithm #nephrology ... #hypokalemia #diagnosis
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Low intake • Metabolic ... thiazide diuretics, Bartter ... syndrome, Gitelman ... potassium #low #nephrology
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Proximal tubule Bartter ... loop of Henle Gitelman ... #Fanconi #Bartter ... #Gitelman #Localization ... Pathophysiology #Nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... #Primary #Metabolic ... Diagnosis #Algorithm #nephrology
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Hypokalemia Differential ... tubular acidosis • Gitelman's ... syndromeBartter's ... syndrome Extrarenal ... Transcellular shift
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Pressure: - Metabolic ... Emesis, Diuretics, Bartter ... syndrome, Gitelman ... Hippurate - Metabolic ... differential #potassium #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... aldosteronism #Metabolic ... Diagnosis #Algorithm #Nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... Hypochloremic metabolic ... • Bartter syndrome ... • Pseudo Bartter-Gitelman ... #nephrology #management
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Syndrome is a rare ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... #nephrology #diagnosis
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Hypomagnesemia - Familial: Bartter ... syndrome and Gitelman ... syndrome, Isolated ... pentamidine), Hypercalcemia ... diagnosis #causes #nephrology