31 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... Hypomagnesemia; hypokalemia ... disturbances (including hypokalemia ... Potassium #Binding #Hyperkalemia
Emergency Management of Hyperkalemia in Adults
Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach
 •
Management of Hyperkalemia ... the Heart • Calcium ... Chloride OR Calcium ... Gluconate IV Shift ... recurrence #Hyperkalemia
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift ... Refeeding Syndrome #Hypokalemia ... potassium #low #pathophysiology
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... membrane: • IV Calcium ... • IV Fluids Shift ... LouLectures #Hyperkalemia
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... MunerMohamed1 #hyperkalemia ... differential #diagnosis #pathophysiology
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
PTH) Effect in Calcium ... and Phosphorus Calcium ... - Net Effect Hypercalcemia ... #Phosphorus #pathophysiology ... #endocrinology
Emergency Therapy of Hyperkalemia
Therapy - Dose and Route - Onset of Action - Duration of Effect
Emergency Therapy of Hyperkalemia ... Effect - Mechanism Calcium ... chloride (10%), Calcium ... Hemodialysis #Hyperkalemia ... #pharmacology #table
Causes of Hypokalemia

Hypokalemia results from abnormal losses, transcellular shifts, or insufficient intake (Table 1).6–8 Abnormal losses
Causes of Hypokalemia ... Hypokalemia results ... transcellular shifts ... insufficient intake (Table ... sole cause of hypokalemia
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... Algorithm • IV calcium ... blocks, QRS axis shift ... , asystole #hyperkalemia
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
the Treatment of Hyperkalemia ... disturbances, shift ... redistributive hyperkalemia ... provoke rebound hypokalemia ... , and Table 3 summarizes