25 results
ANTIBIOTIC SUSCEPTIBILITIES IN INTENSIVE CARE

Antibiotic spectra made simple(r). Version 2, now updated with new bugs &
ANTIBIOTIC SUSCEPTIBILITIES ... INTENSIVE CARE Antibiotic ... Spectra #Spectrum #Coverage ... CriticalCare #Overview #Pharmacology ... Comprehensive Review
Coverage of common antibiotics used in the hospital

For empiric coverage, first define the type of infection,
Coverage of common ... antibiotics used ... infection, then review ... infectiousdisease #antibiotics ... #pharmacology
Tigecycline (IV) - Antibiotics Class Overview

Mechanism: Glycylcycline class - structurally related to Tetracyclines (bacteriostatic).  Only
Tigecycline (IV) - Antibiotics ... Spectrum: Broad coverage ... Notable holes in coverage ... #Pharmacology #Antibiotics ... #Review #Overview
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... • Recent IV potassium ... Beta blockers • Antibiotics ... Intracellular Shift ... #high #nephrology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... MunerMohamed1 #hyperkalemia ... pathophysiology #pharmacology ... #potassium #medications
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... • Recent IV potassium ... Beta blockers • Antibiotics ... Intracellular Shift ... #high #nephrology
Cephalosporin Comparison - Coverage 
1st Generation Cefazolin, Cephalexin 
2nd Generation Cefaclor, Cefotetan, Cefoxitin, Cefuroxime 
3rd Generation
but added MRSA coverage ... commonly used antibiotics ... Here's a simplified review ... Naming #Names #Pharmacology ... #Antibiotics
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... Dialysis Serum potassium ... blocks, QRS axis shift ... , asystole #hyperkalemia ... #potassium #high
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Agents to Treat Hyperkalemia ... patients sensitive to high ... of aspiration #Potassium ... #medications #pharmacology
Hyperkalemia Management Algorithm
 • Treat the cause & optimize hemodynamics and ventilation
 • Reconsider treatment leadingto
Hyperkalemia Management ... and parenteral potassium ... Intracellular K+ Shift ... Algorithm #treatment #potassium ... #high