15 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
edgarvlermamd #Potassium ... #Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... #Hyperkalemia # ... treatment #pharmacology ... #table #comparison
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison ... #binders
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
) MECHANISM: Potassium ... Binder INDICATION ... patiromer) is a potassium ... binder that can ... Pharmacology
Crystalloid Compositon - Normal Saline, Lactated Ringers, PlasmaLyte
#Pharmacology #Crystalloids #Contents #Comparison #Table #Normosol #Plasmalyte #LactatedRingers #NormalSaline
Saline, Lactated Ringers ... , PlasmaLyte #Pharmacology ... #Crystalloids #Contents ... #Comparison #Table
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... MunerMohamed1 #hyperkalemia ... pathophysiology #pharmacology ... #potassium #medications
Crystalloid Fluids - Contents Comparison Table
Normal plasma
0.9% saline (a.k.a. "normal saline" or NS)
0.45% saline (a.k.a. 1/2
Crystalloid Fluids - Contents ... Comparison Table ... KCL D5W Lactated Ringers ... #Comparison #Table ... #pharmacology
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... • Consider K+ binder ... Dialysis Serum potassium ... blocks, QRS axis shift ... #potassium #high
Phosphate Binders
#Pharmacology #Nephro #Phosphate #Phosphorus #Binders #Comparison #Table #Disadvantages #SideEffects
Phosphate Binders ... #Pharmacology ... Phosphate #Phosphorus #Binders ... #Comparison #Table ... Disadvantages #SideEffects
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
130 mEq/L • Potassium ... 6.5 • Caloric content ... Is Dangerous in Hyperkalemia ... transcellular shift ... #pharmacology #