22 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... MunerMohamed1 #hyperkalemia ... #differential # ... pathophysiology #pharmacology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
and sodium • Dosing ... binds magnesium • Dosing ... and calcium • Dosing ... #medications #pharmacology ... #table #comparison
ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
ACEInhibitor #ACEIs #Dosing ... #Conversion #Pharmacology ... #Hypertension # ... PrimaryCare #Comparison #Table
Classification, Differential Diagnosis, and Features of Hyponatremia According to Volume Status 

Hypervolemic hypernatremia 
 - CHF
Classification, Differential ... Glucocorticoid deficit - Hypokalemia ... deficit - Salt-losing ... Classification #Differential ... #Diagnosis #Table
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... Suspicion for Hyperkalemia ... Intracellular Shift ... #differential #
Causes of Hypokalemia

Hypokalemia results from abnormal losses, transcellular shifts, or insufficient intake (Table 1).6–8 Abnormal losses
Causes of Hypokalemia ... Hypokalemia results ... transcellular shifts ... insufficient intake (Table ... #Differential #
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
- Workup and Differential ... with previously stable ... disorders including hypokalemia ... Hyperthyroidism, Hypercalcemia ... Workup #causes #Differential
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... Suspicion for Hyperkalemia ... Intracellular Shift ... #differential #
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Shift of extracellular ... injured muscles -> HYPOTENSION ... per day until stable ... Dialysis for severe hyperkalemia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Shift of extracellular ... injured muscles - HYPOTENSION ... per day until stable ... Rhabdomyolysis #Differential