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management comparison diagnosis causes differential nephrology table algorithm high patiromer rhabdomyolysis binder cardiology classification digoxin effects kayexelate kbinder kbinders lactated
Key Characteristics of Old and New Potassium-Binding Agents - Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd #Potassium #Binding #KBinders #Kayexelate
of Old and New Potassium-Binding ... Agents - Dr. ... #Binding #KBinders ... Comparison #Table #Pharmacology ... #Patiromer #HyperKalemia
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Agents to Treat ... Hyperkalemia Sodium ... to moderate); hypokalemia ... #Binding #Hyperkalemia
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Potassium Binders ... Management of Hyperkalemia ... #Binders #Management ... #Hyperkalemia # ... treatment #pharmacology
Veltassa (Patiromer) MECHANISM: Potassium Binder INDICATION: Treatment of Hyperkalemia FORMULATION: Powder for oral suspension DOSING: 8.4
: Treatment of Hyperkalemia ... who have chronic hyperkalemia ... carry the risk of hyperkalemia ... #Hyperkalemia # ... Pharmacology
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... • Consider K+ binder ... blocks, QRS axis shift ... , asystole #hyperkalemia ... management #algorithm #treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
• LDH ↑ • Hyperkalemia ... Shift of extracellular ... fluid/Lactated ringers ... Monitor potassium ... Dialysis for severe hyperkalemia
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... works by directly binding ... - Hyperkalemia ( ... Because digoxin binds ... , in states of hypokalemia
Emergent Hyperkalemia Treatment Algorithm ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... cardiac membrane Shift ... Remove potassium ... removal of offending agent ... not quickly) #Hyperkalemia
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
Lactated Ringers ... 130 mEq/L • Potassium ... Is Dangerous in Hyperkalemia ... transcellular shift ... NS #comparison #pharmacology
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