20 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC ... shift of K (Succinylcholine ... #differential # ... pathophysiology #pharmacology
Emergency Management of Hyperkalemia in Adults
Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach
 •
Management of Hyperkalemia ... - 6.4 mmol/L - Treatment ... clinical scenario, ECG ... Gluconate IV Shift ... recurrence #Hyperkalemia
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... ECG changes, weakness ... injury, etc) ECG ... cardiac membrane Shift ... not quickly) #Hyperkalemia
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... potassium and ECG ... blocks, QRS axis shift ... , asystole #hyperkalemia ... management #algorithm #treatment
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Transcellular Shifts ... plasma insulin (treatment ... ß-Adrenergic agonists, Hypokalemic ... #Causes #differential
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... • LDH ↑ • Hyperkalemia ... Shift of extracellular ... Treatment of underlying ... Rhabdomyolysis #Differential
Mesenteric Ischemia - Differential Diagnostic Schema
Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA)
Acute
 - Venous
Mesenteric Ischemia - Differential ... inflammation (e.g ... Dissection, ASCVD, True hypovolemia ... ), Meds/Treatments ... Ischemia #Schema #Differential
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Shift of extracellular ... oxidative iniury Treatment ... Dialysis for severe hyperkalemia ... Summary #causes #treatment
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
Medications for the Treatment ... goals of acute treatment ... disturbances, shift ... , changes on ECG ... #Treatment
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
Metabolic causes (e.g ... ., hypokalemia, ... disease, Drugs (e.g ... Treatment is aimed ... Nephrology #Diagnosis #Differential