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management diagnosis hyperkalemia algorithm potassium infections opportunistic prevention differential idsa medications cardiology coccidioides coccidioidomycosis comparison criticalcare foamed lysis syndrome table
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC ... shift of K (Succinylcholine ... MunerMohamed1 #hyperkalemia ... pathophysiology #pharmacology
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... potassium and ECG ... blocks, QRS axis shift ... #potassium #high ... management #algorithm #treatment
Emergency Management of Hyperkalemia in Adults Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach •
Management of Hyperkalemia ... - 6.4 mmol/L - Treatment ... clinical scenario, ECG ... Gluconate IV Shift ... recurrence #Hyperkalemia
Emergent Hyperkalemia Treatment Algorithm ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... ECG changes, weakness ... injury, etc) ECG ... cardiac membrane Shift ... not quickly) #Hyperkalemia
Hyperkalemia Management Algorithm • Treat the cause & optimize hemodynamics and ventilation • Reconsider treatment leadingto
Hyperkalemia Management ... • Reconsider treatment ... Intracellular K+ Shift ... Management #Algorithm #treatment ... #potassium #high
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
cytotoxic therapies in high-burden ... ) occur in high ... malignancies Treatments ... 6L/day) • For hyperkalemia ... with Ca only if EKG
Medications for the Treatment of Hyperkalemia The goals of acute treatment are to prevent potentially life-threatening cardiac
Medications for the Treatment ... goals of acute treatment ... disturbances, shift ... , changes on ECG ... #Treatment
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 SGLT2 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... CV mortality in high ... AKI (likely from hypovolemia ... GU infections (e.g ... SGLT2 #Inhibitors #Pharmacology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... organ damage • Treatment ... Spontaneous if high ... hydration - Hyperkalemia ... unless worrisome EKG
Evaluation and Management of Hypokalemia Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
Hypokalemia is ... warranting urgent treatment ... electrocardiography (ECG ... transcellular shifts ... Identification and treatment
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