12 results
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
the basis of the potassium-to-creatinine ... creatinine) • Cell shift ... Non-reabsorbable anion effect ... #urine #potassium ... algorithm #diagnosis #nephrology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... 15 g QD • Side Effects ... patients sensitive to high ... of aspiration #Potassium ... pharmacology #table #comparison
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... A urine K/Cr ratio ... • Diarrhea A urine ... urinary losses: • High ... #nephrology #low
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... • Recent IV potassium ... Intracellular Shift ... diagnosis #causes #potassium ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... • Recent IV potassium ... Intracellular Shift ... diagnosis #causes #potassium ... #high #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Decreased intake (rare cause in isolation)
GI loss - Urine loss
Causes of Hypokalemia ... isolation) GI loss - Urine ... Transcellular shift ... renin, High aldosterone ... #Nephrology #Differential
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
- Hyperkalemia ( ... high potassium levels ... ) is a side effect ... , in states of hypokalemia ... Pathophysiology #cardiology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
130 mEq/L • Potassium ... Is Dangerous in Hyperkalemia ... transcellular shift ... densa receives high ... Decreased GFR, urine
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
mineralocorticoid-like effect ... to diarrhea, a high ... high in kidney ... of sodium and potassium ... #Algorithm #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Weakness - Dark urine ... Shift of extracellular ... hour with goal urine ... Monitor potassium ... causes #treatment #nephrology