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management diagnosis hyperkalemia differential high algorithm causes nephrology checklist chf heartfailure pharmacology rhabdomyolysis cardiacglycoside cardiogenic classification clinical complexes digitaliseffect digoxintoxicity
EKG showing prominent U waves due to hypokalemia. Serum potassium 2.0. #EKG #emergencymedicine #criticalcare #cardiology #internalmedicine
U waves due to hypokalemia ... Serum potassium ... emergencymedicine #criticalcare ... #cardiology #internalmedicine
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
- Hyperkalemia ( ... high potassium levels ... , in states of hypokalemia ... (or low potassium ... Pathophysiology #cardiology
Hyperkalemia Treatment Options Stabilize cardiac membrane: • IV Calcium (peaks 5-10 minutes) Decrease potassium concentration: • IV Fluids Shift
Hyperkalemia Treatment ... minutes) Decrease potassium ... • IV Fluids Shift ... potassium intracellularly ... LouLectures #Hyperkalemia
Checklist Approach to Hypokalemia Consider risk factors for arrhythmia: - EKG changes (especially QT prolongation) - Digoxin
Checklist Approach to Hypokalemia ... prolongation) - Digoxin ... route = severe hypokalemia ... /hr for severe hypokalemia ... #Management #CriticalCare
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... : • Digoxin ... • Recent IV potassium ... Intracellular Shift ... diagnosis #causes #potassium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... : • Digoxin ... • Recent IV potassium ... Intracellular Shift ... diagnosis #causes #potassium
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... Dialysis Serum potassium ... blocks, QRS axis shift ... #potassium #high ... management #algorithm #treatment
Hyperkalemia Management Algorithm • Treat the cause & optimize hemodynamics and ventilation • Reconsider treatment leadingto
• Reconsider treatment ... and parenteral potassium ... Intracellular K+ Shift ... Management #Algorithm #treatment ... #potassium #high
Medications for the Treatment of Hyperkalemia The goals of acute treatment are to prevent potentially life-threatening cardiac
Medications for the Treatment ... goals of acute treatment ... disturbances, shift ... warranted because treatment ... #Treatment
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 The chemical formula of Digoxin is C41 H64 O14. Digoxin (Cardiac glycoside) reversibly inhibits the sodium-potassium-ATPase, causing
inhibits the sodium-potassium-ATPase ... intracellular potassium ... conditions (eg, hypokalemia ... Hypokalemia is a ... the successful treatment
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