15 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
of Old and New Potassium-Binding ... edgarvlermamd #Potassium ... KBinders #Kayexelate #Comparison ... #Pharmacology #Patiromer ... #HyperKalemia #
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... polystyrene sulfonate • Patiromer ... #treatment #pharmacology ... #table #comparison
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
Veltassa (Patiromer ... ) MECHANISM: Potassium ... INDICATION: Treatment ... ) is a potassium ... #Potassium #Binder
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... minutes) Decrease potassium ... • IV Fluids Shift ... potassium intracellularly ... LouLectures #Hyperkalemia
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Agents to Treat Hyperkalemia ... Patiromer (Veltassa ... of aspiration #Potassium ... pharmacology #table #comparison
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... Dialysis Serum potassium ... blocks, QRS axis shift ... #potassium #high ... management #algorithm #treatment
Hyperkalemia Management Algorithm
 • Treat the cause & optimize hemodynamics and ventilation
 • Reconsider treatment leadingto
• Reconsider treatment ... and parenteral potassium ... Intracellular K+ Shift ... Management #Algorithm #treatment ... #potassium #high
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
Medications for the Treatment ... goals of acute treatment ... disturbances, shift ... warranted because treatment ... #Treatment
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Stabilization Treatments ... Redistribution Treatments ... Elimination Treatments ... effectiveness - Patiromer ... #potassium #nephrology
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... Treatment Algorithm ... cardiac membrane Shift ... Remove potassium ... not quickly) #Hyperkalemia