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management hyperkalemia causes differential nephrology blood hematology product rhabdomyolysis algorithm comparison k medications pharmacology summary transfusion transfusions
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... patients sensitive to high ... of aspiration #Potassium ... #Binding #Hyperkalemia ... #pharmacology #table
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... phlebotomy High ... Intracellular Shift ... #causes #potassium ... #high #nephrology
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
• Consider K+ binder ... blocks, QRS axis shift ... #potassium #high ... #diagnosis #management ... #algorithm #treatment
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... phlebotomy High ... • Recent IV potassium ... Intracellular Shift ... #high #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Shift of extracellular ... fluid/Lactated ringers ... Monitor potassium ... per day until stable
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
- Differential Diagnosis ... Shift of extracellular ... Monitor potassium ... per day until stable ... Dialysis for severe hyperkalemia
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Elimination (see Table ... : • K-Binding ... #Diagnosis #Management ... #Treatment #potassium
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
High mortality. ... , Hyperkalemia: ... Citrate in RBCs binds ... products contain potassium ... #Transfusion #diagnosis
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
High mortality. ... , Hyperkalemia: ... Citrate in RBCs binds ... products contain potassium ... #Transfusions #diagnosis
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