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diagnosis differential hyperkalemia nephrology management pharmacology rhabdomyolysis algorithm binders binding classification complexes drugs effects hypomagnesemia hypomg lactated lr normal ns
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Intracellular Shift ... - Tumor lysis syndrome ... Medications 2. ... differential #diagnosis #causes ... #potassium #high
Hyperkalemia Management Algorithm • Treat the cause & optimize hemodynamics and ventilation • Reconsider treatment leadingto
• Treat the cause ... • Reconsider treatment ... and parenteral potassium ... Intracellular K+ Shift ... #potassium #high
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... patients sensitive to high ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Intracellular Shift ... - Tumor lysis syndrome ... Medications 2. ... differential #diagnosis #causes ... #potassium #high
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
- Shift from extracellular ... - Insulin (high ... renal Fanconi syndrome ... hypomagnesemia #Medications ... diagnosis #nephrology #Causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... - Compartment syndrome ... Shift of extracellular ... Monitor potassium ... Diagnosis #Management #causes
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia ... Management #Summary #causes ... #treatment
Causes of Hyperkalemia - Differential Diagnosis Framework • Cellular Shift: - Exercise
Causes of Hyperkalemia ... Framework • Cellular Shift ... hyperosmolality - Medications ... Differential #Diagnosis #Causes ... #potassium #high
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
Saline (NS) - Comparison ... 130 mEq/L • Potassium ... Is Dangerous in Hyperkalemia ... transcellular shift ... densa receives high
Premature Ventricular Complexes (PVC's) - Summary Framework Why PVCs? Can be the first manifestation of cardiac
Inherited arrhythmia syndromes ... (e.g., long QT syndrome ... Hypomagnesemia • Hypokalemia ... more intensive treatment ... #differential #cardiology
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