20 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... (TLS) and Treatment ... 8.0 mg/dL • Potassium ... Treatment of TLS ... #TumorLysis #Syndrome
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift ... - Refeeding Syndrome ... #Hypokalemia ... #potassium #low
Causes of Hypokalemia

Hypokalemia results from abnormal losses, transcellular shifts, or insufficient intake (Table 1).6–8 Abnormal losses
Causes of Hypokalemia ... transcellular shifts ... insufficient intake (Table ... significantly lower potassium ... rarely the sole cause
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - Causes ... Guillain-Barré syndrome ... Hyperreflexia: • Hypocalcemia ... Hyperthyroidism, Serotonin syndrome ... differential #diagnosis #table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... HIV, Influenza, TSS ... Shift of extracellular ... Monitor potassium ... per day until stable
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
HIV, Influenza, TSS ... Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia ... Management #Summary #causes
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... ); nausea, vomiting ... of aspiration #Potassium ... #pharmacology #table ... #comparison #binders
Hyperkalemia Management Algorithm
 • Treat the cause & optimize hemodynamics and ventilation
 • Reconsider treatment leadingto
• Treat the cause ... • Reconsider treatment ... and parenteral potassium ... Intracellular K+ Shift ... #potassium #high
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
Medications for the Treatment ... goals of acute treatment ... disturbances, shift ... , and Table 3 summarizes ... #Treatment
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... cyclosilicate #Potassium ... #treatment #pharmacology ... #table #comparison