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Posterior Reversible Encephalopathy Syndrome (PRES) - Diagnosis
Clinical Features:
 • Altered mental status (Either lethargy, confusion, or
Posterior Reversible Encephalopathy ... Syndrome (PRES) ... Altered mental status ... agitation) • Seizures ... Immunomodulatory meds
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Posterior Reversible Encephalopathy ... the underlying cause ... : Treat with AEDs ... until cause identified ... #Reversible #Encephalopathy
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Movement disorders, Seizure ... Meningitis, Myelopathy, Encephalopathy ... Cerebrovascular Disease, PRES ... autoantibodies that will cause ... Secondary prevention (statin
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
Altered mental status ... pupil (AACG) • Systemic ... fever, myalgia), seizures ... • Hypertensive encephalopathy ... #neurology #PHANTOMS
Causes of Status Epilepticus in Adults
METABOLIC DISTURBANCES
Hepatic encephalopathy
Hypocalcemia
Hypoglycemia or hyperglycemia
Hyponatremia
Uremia
INFECTIOUS PROCESSES
Central nervous system abscess
Encephalitis
Meningitis
WITHDRAWAL SYNDROMES
Alcohol
Antiepileptic drugs
Baclofen
Barbiturates
Benzodiazepines
CENTRAL
Causes of Status ... DISTURBANCES Hepatic encephalopathy ... Central nervous system ... #Epilepticus #Seizures ... #neurology
The algorithm below shows how pre-test probability could be combined with various criteria to determine which
The algorithm below ... and lowers the seizure ... acyclovir to all encephalopathic ... HSV PCR would cause ... and immunologic status