10 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Agents - Dr. ... #Binding #KBinders ... #Kayexelate #Comparison ... Pharmacology #Patiromer #HyperKalemia ... #Nephrology #Agents
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... #Binders #Management ... #Hyperkalemia # ... pharmacology #table #comparison ... #nephrology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Agents to Treat ... of aspiration #Potassium ... pharmacology #table #comparison ... #binders
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... • Consider K+ binder ... Dialysis Serum potassium ... blocks, QRS axis shift ... #potassium #high
Table 22 provides the characteristics of various phosphate-binding agents.
#Pharmacology #Nephrology #Phosphate #Phosphorus #Binders #Comparison #Table #Disadvantages
phosphate-binding agents ... #Pharmacology #Nephrology ... Phosphate #Phosphorus #Binders ... #Comparison #Table
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... Inexpensive - Treats hypocalcemia ... #Phosphate #Binders ... #Table #Comparison ... #Pharmacology #Nephrology
KDIGO Treatment algorithm for management of acute hyperkalemia in the emergency department
 • Place on cardiac
management of acute hyperkalemia ... • Consider K+ binder ... Consider dialysis #hyperkalemia ... algorithm #treatment #potassium ... #high #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
• LDH ↑ • Hyperkalemia ... Shift of extracellular ... fluid/Lactated ringers ... Monitor potassium ... causes #treatment #nephrology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
Saline (NS) - Comparison ... 130 mEq/L • Potassium ... Is Dangerous in Hyperkalemia ... transcellular shift ... Normal #Saline #NS #comparison
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Causes of Hyperkalemia ... extracellular shift ... noncardioselective agents ... Diagnosis #High #Potassium ... #Classification