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diagnosis hyperkalemia table nephrology treatment causes high medications algorithm agents binding dosing hematology hypertension hypokalemia inotropes pathophysiology primarycare product reactions
Key Characteristics of Old and New Potassium-Binding Agents - Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd #Potassium #Binding #KBinders #Kayexelate
of Old and New Potassium-Binding ... edgarvlermamd #Potassium ... #Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Potassium Binders ... for Management ... #Binders #Management ... Hyperkalemia #treatment #pharmacology ... #table #comparison
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... Benyzlpenicillin, blood ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #potassium #medications
Hyperkalemia Treatment Options Stabilize cardiac membrane: • IV Calcium (peaks 5-10 minutes) Decrease potassium concentration: • IV Fluids Shift
minutes) Decrease potassium ... • IV Fluids Shift ... potassium intracellularly ... peaks 1-2h) • Blood ... #Hyperkalemia #management
ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
Antihypertensive Dose Comparison ... Monitor BP, potassium ... Dosing #Conversion #Pharmacology ... #Hypertension #Management ... #PrimaryCare #Comparison
REBEL Review 71: Treatment of Thyroid Storm Propranolol Esmolol Propylthiouracil (PTU) Methimazole Saturated Solution of Potassium
Saturated Solution of Potassium ... hyperthyroidism #table #management ... #treatment #pharmacology ... #comparison #Dosages
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
Saline (NS) - Comparison ... 130 mEq/L • Potassium ... transcellular shift ... Normal #Saline #NS #comparison ... #pharmacology #
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... • Consider K+ binder ... Dialysis Serum potassium ... blocks, QRS axis shift ... #hyperkalemia #potassium
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison ... #binders
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Crush injury • Blood ... • Recent IV potassium ... Intracellular Shift ... Blood transfusion
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