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diagnosis causes comparison hematology high hypokalemia pathophysiology reactions treatment algorithm druginduced effects gitelman lactated lr medications normal ns rhabdomyolysis ringers
Hyperkalemia Treatment Options Stabilize cardiac membrane: • IV Calcium (peaks 5-10 minutes) Decrease potassium concentration: • IV Fluids Shift
Hyperkalemia Treatment ... • IV Fluids Shift ... peaks 1-2h) • Blood ... #management #potassium ... #nephrology
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Potassium Binders ... for Management ... #Binders #Management ... treatment #pharmacology ... table #comparison #nephrology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... Benyzlpenicillin, blood ... #differential # ... pathophysiology #pharmacology ... #potassium #medications
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Crush injury • Blood ... Intracellular Shift ... #differential # ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Crush injury • Blood ... Intracellular Shift ... #differential # ... #high #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Framework and Management ... UA positive for blood ... Shift of extracellular ... Monitor potassium ... causes #treatment #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
patients with hypokalemia ... creatinine) • Cell shift ... effective arterial blood ... #differential # ... algorithm #diagnosis #nephrology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
130 mEq/L • Potassium ... Can give with blood ... Is Dangerous in Hyperkalemia ... transcellular shift ... NS #comparison #pharmacology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Citrate in RBCs binds ... Blood products contain ... potassium from ... #diagnosis #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Hypocalcemia, Hyperkalemia ... Citrate in RBCs binds ... Blood products contain ... potassium from ... #diagnosis #management
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