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differential causes nephrology table treatment high coccidioides coccidioidomycosis rhabdomyolysis antifungal antifungals antipsychotic binders binding bloodpressure classification diuresis diuretics druginduced encephalopathy
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Increased EC shift ... #differential #diagnosis ... pathophysiology #pharmacology ... #potassium #medications
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Agents to Treat ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... reactions Common Drugs ... Intracellular Shift ... Medications 2. ... #causes #potassium
Neurological Side Effects of Antipsychotic Drugs Acute dystonia - Spasm of muscles of tongue, face, neck, back
are diagnostic ... reduction; change medication ... #Medications #SideEffects ... #pharmacology # ... management
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... reactions Common Drugs ... • Recent IV potassium ... Intracellular Shift ... Medications 2.
Intern Pocket Cards - Inpatient Blood Pressure Management Guide ß-blockers: • Metoprolol, Carvedilol, Labetalol • Bradycardia, heart
Blood Pressure Management ... Valsartan • AKI, hyperkalemia ... #Inpatient #pharmacology ... #table #agents ... #internship #comparison
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
and Management ... Drugs (Statins), ... Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Framework and Management ... - Toxins - Drugs ... Shift of extracellular ... Monitor potassium
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
extracellular shift ... noncardioselective agents ... Drug-associated: ... #Differential #Diagnosis ... #High #Potassium
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Immunosuppressive agents ... Blood transfusion, Hypercalcemia ... Electrolyte abnormality, Medication ... /Drug toxicity, ... #management #neurology
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