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management causes hyperkalemia pathophysiology nephrology algorithm cardiology disease rheumatology syndrome american chagas classification criticalcare druginduced drugs erythematosus foamed gastroenterology hematology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Diagnosis Framework ... phlebotomy High ... Intracellular Shift ... #potassium #high
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Dialysis Serum potassium ... blocks, QRS axis shift ... #hyperkalemia #potassium ... #high #diagnosis ... management #algorithm #treatment
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
the basis of the potassium-to-creatinine ... creatinine) • Cell shift ... hypokalemia #urine #potassium ... #differential # ... algorithm #diagnosis
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Diagnosis Framework ... phlebotomy High ... Intracellular Shift ... #potassium #high
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Rhabdomyolysis - Differential ... Diagnosis and Management ... Shift of extracellular ... Monitor potassium ... #Diagnosis #Management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... Dermatomyositis Clinical ... Shift of extracellular ... Monitor potassium
Peritonitis - Spontaneous vs Secondary vs Peritoneal Dialysis Associated Peritonitis Spontaneous Bacterial Peritonitis • Cirrhosis (high SAAG)
• Cirrhosis (high ... PMN > 250 • Treatment ... at least 2): 1) Clinical ... Secondary #Peritoneal #diagnosis ... #differential #
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... Left Shift: • ... Metamyelocyte (Left Shift ... with moderate and high ... #Bandemia #differential
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
• These shifts ... may cause severe clinical ... hyperparathyroidism Treatment ... Syndrome #Nutrition #Differential ... #Diagnosis #Pathophysiology
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