35 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... and sodium • Dosing ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... minutes) Decrease potassium ... • IV Fluids Shift ... Albuterol (4-8x dose ... LouLectures #Hyperkalemia
ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
Antihypertensive Dose ... Monitor BP, potassium ... ACEInhibitor #ACEIs #Dosing ... #Conversion #Pharmacology ... PrimaryCare #Comparison #Table
REBEL Review 71: Treatment of Thyroid Storm 

Propranolol 
Esmolol 
Propylthiouracil (PTU) 
Methimazole 
Saturated Solution of Potassium
REBEL Review 71: Treatment ... Saturated Solution of Potassium ... hyperthyroidism #table ... #pharmacology # ... comparison #Dosages #dosing
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... #differential #diagnosis ... pathophysiology #pharmacology ... #potassium #medications
Emergency Therapy of Hyperkalemia
Therapy - Dose and Route - Onset of Action - Duration of Effect
Emergency Therapy of Hyperkalemia ... Therapy - Dose ... Hemodialysis #Hyperkalemia ... #management #pharmacology ... #table #treatment
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
Medications for the Treatment ... goals of acute treatment ... disturbances, shift ... , and Table 3 summarizes ... #Treatment
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
maximum daily dose ... since they are not able ... Generally, the initial dose ... restricted due to hypercalcemia ... #Dosing #Pharmacology
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... cardiac membrane Shift ... -2 hours Dose ... ~2 hours Dose ... Remove potassium
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... cyclosilicate #Potassium ... #treatment #pharmacology ... #table #comparison