16 results
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... to Systemic Diseases ... Iron deficiency anemia ... Differential #Diagnosis #Algorithm ... #causes
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Primary Causes ... Liver Function Tests ... renal failure/uremia ... Pruritus #primary #secondary ... #causes
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days)
Exclude:
1. Causes of acute diarrhea
2. Lactose intolerance
3.
Algorithm for the ... Causes of acute ... Systemic disease ... #management #algorithm ... #workup #diagnosis
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
hypotension - Nausea ... , vomiting, diarrhea ... mild normocytic anemia ... Autoimmune thyroid disease ... Central nervous system
Primary and Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Primary (Essential) (95%) - Onset between age
Causes of Hypertension ... Differential Diagnosis Algorithm ... taken at home, work ... Hyperthyroidism (mainly systolic ... Differential #Diagnosis #Algorithm
Whipple Disease (Tropheryma whipplei) - Diagnosis and Management 

Caused by: Tropheryma whipplei

Symptoms and Signs:
1. Migratory poly/oligoarthralgia
Whipple Disease ... Diagnosis and Management ... Caused by: ... Intermittent diarrhea ... #diagnosis #algorithm
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
rainwater catchment systems ... non-productive cough, nausea ... , vomiting and diarrhea ... agglutination - test ... diagnosis #treatment #management
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... value is low, tests ... result in severe anemia ... leukocytosis with a left shift ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... • Infectious diarrhea ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... DDX - Other causes
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Liver Function Tests ... renal failure/uremia ... #Pruritus #secondary ... #systemic #generalized ... #causes