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management hematology signs symptoms arteritis behcet cryofibrinogenemia differential disease gca giantcell gravis hemeonc hemophagocytic hlh lymphohistiocytosis myasthenia polychondritis relapsing sapho
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... ulceration • Ocular ... skin injury) • Neurologic ... (Clinical Dx). ... signs #symptoms #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
: • A clinical ... out other causes ... heel, and lower jaw ... #Rheumatology # ... #Dermatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Ocular- 50%: Ptosis ... myasthenia Diagnosis ... Bedside: ice pack test ... /Edrophonium test ... #management #neurology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... the “Chewing gum test ... identifies 85 to 95% of cases ... them, but urgent rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
pulmonary emboli, and ocular ... : • + Clinical ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... scalp tenderness, jaw ... affects the skin, neurologic ... tract, and often causes ... #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
the most common clinical ... chondritis • Ocular ... : • Clinical tests ... Polychondritis #rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... caused by uncontrolled ... Clinical Presentation ... Emerging therapies: JAK ... #Management #Hematology
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