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differential neurology guillain loss alopecia anemia blood caudaequina common cvid dermatology effusions equina gbs guillainbarre hair hairloss hearing hypogammaglobulinemia immunodeficiency
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - HCV - HIV ... CMV) • Epstein-Barr ... Anemia #oncology #hematology ... #diagnosis #management
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
Cauda Equina Syndrome ... - Emergency Causes ... cord • Guillain-Barre ... • Provocative Tests ... #causes #neurology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Diagnosis: • ... nerve roots and cauda ... #Syndrome #diagnosis ... #management #treatment
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Causes of Knee Effusions ... - Differential Diagnosis ... #Effusions #causes ... #differential #diagnosis ... #msk #physicalexam
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... and sensitive tests ... nerve roots and cauda ... #Syndrome #diagnosis ... #management #neurology
Hearing Loss - Differential Diagnosis Framework Hearing Loss Types: • Conductive • Sensorineural • Mixed Presbycusis is the most common type
- Differential Diagnosis ... II ○ Susac’s syndrome ... Noise trauma ○ MS ... Labyrinthitis ○ Epstein-Barr ... #Differential #Diagnosis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
DDX - Other causes ... infections (Epstein-Barr ... syndrome, HIV) ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
- Differential Diagnosis ... Alopecia mucinosa, Aplasia ... , Loose anagen syndrome ... disease • Pull test ... Initial Laboratory Tests
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... Diagnosis #Management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
indirect Coombs test ... due to marrow aplasia ... Extremely rare - HIV ... #Transfusions #diagnosis ... #management #hematology
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