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differential rheumatology classification management algorithm pathophysiology physicalexam syndromes agglutinin anemia arterial bee bleeding cold cryofibrinogenemia cryoglobulinemia cryoglobulins dermatology disease effusions
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
methotrexate) • Drugs Autoimmune ... Quinidine • HIT ... Non-lmmune: • HELLP Syndrome ... HUS • DIC • Vasculitis ... #Hematology
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Causes of Knee Effusions ... - Differential Diagnosis ... Non-weight bearing ... #Effusions #causes ... #msk #physicalexam
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... HBV infection, HIV ... infection • Autoimmune ... Labs/Diagnosis:
Hearing Loss - Differential Diagnosis Framework Hearing Loss Types: • Conductive • Sensorineural • Mixed Presbycusis is the most common type
Diagnosis Framework ... • Stroke • Vasculitis ... II ○ Susac’s syndrome ... Noise trauma ○ MS ... #Differential #Diagnosis
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Asthma Tugs (vasculitis ... / autoimmune): ... Hypereosinophilic Syndrome ... #Causes #hematology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
OnePager Summary Autoimmune ... ANCA vasculitis ... sinus, nasal, hearing ... anti-GBM) Other tests ... Goodpasture's cause
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... an underlying autoimmune ... pachymeningitis • HIV ... sensorineural hearing ... consistent with MS
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... - Differential Diagnosis ... Palpable Rash: - Autoimmune ... Vasculitis (lupus ... Fecal occult blood test
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... ) • Cutaneous vasculitis ... Nephrogenic DI Hematologic ... : 2% Systemic Vasculitis ... phenomenon (16%) MSK
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
by neutrophilic autoimmune ... nephrotic/nephritic syndrome ... arthritis (especially knees ... and ankles) #HSP ... Pathophysiology #Diagnosis
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