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Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis ... Rash Secondary ... Skin rash and malaise ... The signs and symptoms ... resembling rashes caused
Stages of Syphilis
Early Primary:
 • Painless chancre
 • Regional lymphadenopathy
Early Secondary:
 • Fever, malaise
 • Rash
Stages of Syphilis ... lymphadenopathy Early Secondary ... Fever, malaise • Rash ... lesions in bone, skin ... #signs #diagnosis
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Secondary Syphilis ... - Rash, pink ... exposure to or symptoms ... granuIomas on skin ... of Infectious Diseases
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
Primary and secondary ... hypotension - Nausea ... Autoimmune thyroid disease ... disorders: - Pale skin ... Insufficiency #Signs
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy
Malignancies
 - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms
Infections
 -
MIAMI Mnemonic for Differential ... lymphomas, metastases, skin ... venereum, primary and secondary ... syphilis, tuberculosis ... sarcoidosis Iatrogenic causes
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Screen for secondary ... (common causes ... organ-specific signs ... , skin or esophageal ... Disorders #Algorithm #Differential
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
responsible for most cases ... weight loss • Skin ... : Rash is the most ... infected without symptoms ... stages #diagnosis #management
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Papulosquamous Skin ... Rash - Differential ... Auspitz sign, Koebner's ... Syphilis - Red ... Diagnosis #Algorithm #causes
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... arthritis - with the skin ... inflammation is secondary ... should have other symptoms ... like “butterfly rash
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis