64 results
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... thrombophlebitis Skin ... band syndrome • Shin ... Brittle nails - Skin ... skin • Inflammation
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... Scleroderma Thickened skin ... arthritis Discoid skin ... #skin #rashes # ... #rheumatology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
rubbing of the skin ... Staphylococcal scalded skin ... syndrome, caused ... #PhysicalExam #Video ... Clinical #SJS #skin
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Polyneuropathy, Cranial nerve ... lesions Abdominal pain ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Physiologic Skin Changes in Pregnancy - Differential Diagnosis Algorithm

Face
 • Melasma
Abdomen
 • Linea Nigra 
Hormone induced
Physiologic Skin ... number (probable) Skin ... • Chadwick's sign ... normal #Pregnancy #skin ... Diagnosis #Algorithm #causes
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... organ-specific signs ... symptoms (eg, skin ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
hyperglycemic crises ... diabetes Key signs ... hypovolemia (dry MM, skin ... diffuse abdominal pain
Clinical manifestations of anaphylaxis. 
Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache
Angioedema: Lips, tongue, orbit,
intestines, extremities Skin ... (Skin and Mucosa ... arrest GI (>40%): Nausea ... edema, abdominal pain ... #anaphylaxis #signs
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
manifestations Skin ... Inflammation of skin ... granulomas under skin ... inflammation tends to cause ... pathophysiology #signs
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin